A comparison of the protective effect of vaccination and clinical features between the SARS-CoV-2 wild-type strain and Delta (B.1.617.2) variant

比较SARS-CoV-2野生型毒株和Delta(B.1.617.2)变异株的疫苗接种保护效果和临床特征

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Abstract

INTRODUCTION: This study aimed to investigate the clinical features and vaccine effectiveness of patients with the SARS-CoV-2 wild-type strain and the Delta variant. METHODS: We retrospectively evaluated patients with the SARS-CoV-2 wild-type strain and the Delta variant. RESULTS: The Delta-variant group showed a higher infection rate in minors, who had higher incidence of anosmia or dysgeusia and shorter incubation period. Unvaccinated patients had a 15.59-fold higher risk of severe classification than vaccinated patients. The viral clearance time was significantly shorter in the Delta-variant group. CONCLUSIONS: The Delta-variant group show higher transmissibility, and vaccination reduces the incidence of severe classification and promotes viral clearance.

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