Abstract
INTRODUCTION: The aim of the study was to explore the clinical efficacy and safety of intravenous thrombolysis and bridging artery thrombectomy for hyperacute ischemic stroke with unknown onset time. METHODS: One hundred and twenty-eight patients with hyperacute cerebral infarction and without a clear time of onset were randomly divided into intravenous thrombolysis (n = 66) and bridging artery thrombectomy groups (n = 62). RESULTS: In the intravenous thrombolysis group, 37 patients' vessels had recanalization, 32 patients' 24-hour National Institute of Health Stroke Scale (NIHSS) score improved, and 42 patients' 90-day modified Rankin Scale (mRS) score was good. In the bridging artery thrombectomy group, 62 patients' vessels had recanalization, 28 patients' 24-hour NIHSS score improved, and 38 patients' 90-day mRS score was good. CONCLUSIONS: The benefits and adverse events between intravenous thrombolysis and bridging artery thrombectomy for ischemic stroke with unknown time of onset are similar.