Abstract
PURPOSE: This comprehensive review thoroughly explores the clinical significance of the palmomental reflex (PMR) in neurological disorders. PMR is a primitive reflex that, when reemerging in adults, indicates underlying neurological dysfunction. METHOD: The article elaborates on the clinical assessment techniques, neurophysiological basis, and applications of PMR in various neurological disorders, including neurodegenerative diseases, cerebrovascular disorders, traumatic brain injury, and multiple sclerosis. FINDING: By understanding the modulation and suppression mechanisms of PMR, valuable insights into the specific neurological impairments associated with these disorders can be gained. CONCLUSION: The potential of PMR as a diagnostic marker, prognostic indicator, and treatment monitoring tool is increasingly evident.