IgA negative immunofluorescence in diagnoses of adult-onset Henoch-Schönlein purpura

成人发病型亨诺赫-舍恩莱因紫癜诊断中的IgA阴性免疫荧光

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Abstract

We describe two cases of young adult men presenting with diffuse petechial rash and gastrointestinal disturbances. They were found to have leukocytoclastic vasculitis without immunoglobulin A findings under direct immunofluorescence on skin biopsy histopathology performed over a week after the appearance of lesions. Henoch Schönlein purpura (HSP) was diagnosed based upon the clinical presentation as well as the leukocytoclastic vasculitis biopsy findings.

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