Abstract
Sjögren's syndrome (SS) is an autoimmune disorder that results in chronic inflammatory and degenerative alterations in the exocrine glands and systemic organs, with an estimated incidence rate of 6.92 per 100 000 person-years. This case illustrates an uncommon correlation in a patient who developed new-onset seizures during the peripartum period, primary Sjögren's disease (pSS), and chronic renal artery stenosis. pSS may go undetected when it manifests with other systemic disorders without classical symptoms. This paper emphasizes the distinct characteristics of pSS in pregnant women, proposing that the RAS, identified prior to the diagnosis of SS and new-onset seizure during this admission, may signify vasculitis consequence.