Abstract
Pruritus ani is a neurofunctional dermatological condition frequently encountered in proctology, characterized by persistent perianal itching that can significantly compromise the patient's quality of life. This case report details a 48-year-old male patient with a 4-year history of perianal itching. Following local excision of the perianal skin, the wound healed satisfactorily on postoperative day 32 and achieved complete resolution of itching symptoms, with the patient attaining full recovery by day 40, thereby demonstrating remarkable clinical efficacy. Additionally, this report reviews relevant literature to investigate the diagnostic and therapeutic approaches for pruritus ani.