Abstract
The increase of diabetic retinopathy patients and diabetic mellitus worldwide yields lot of challenges to ophthalmologists in the screening of diabetic retinopathy. Different signs of diabetic retinopathy were identified in retinal images taken through fundus photography. Among these stages, the early stage of diabetic retinopathy termed as microaneurysms plays a vital role in diabetic retinopathy patients. To assist the ophthalmologists, and to avoid vision loss among diabetic retinopathy patients, a computer-aided diagnosis is essential that can be used as a second opinion while screening diabetic retinopathy. On this vision, a new methodology is proposed to detect the microaneurysms and non-microaneurysms through the stages of image pre-processing, candidate extraction, feature extraction, and classification. The feature extractor, generalized rotational invariant local binary pattern, contributes in extracting the texture-based features of microaneurysms. As a result, our proposed system achieved a free-response receiver operating characteristic score of 0.421 with Retinopathy Online Challenge database.