Abstract
Glaucoma is a silent progressive eye disease that is among the leading causes of irreversible blindness. Early detection and proper treatment of glaucoma can limit severe vision impairments associated with advanced stages of the disease. Periodic automatic screening can help in the early detection of glaucoma while reducing the workload on expert ophthalmologists. In this work, a wavelet-based glaucoma detection algorithm is proposed for real-time screening systems. A combination of wavelet-based statistical and textural features computed from the detected optic disc region is used to determine whether a retinal image is healthy or glaucomatous. Two public datasets having different resolutions were considered in the performance analysis of the proposed algorithm. An accuracy of 96.7% and area under receiver operating curve (AUC) of 94.7% were achieved for the high-resolution dataset. Analysis of the wavelet-based statistical and textural features using three different methods showed their relevance for glaucoma detection. Furthermore, the proposed algorithm is shown to be suitable for real-time applications as it requires less than 3 s for processing the high-resolution retinal images.