Abstract
BACKGROUND: Germ cell tumors (GCTs) are neoplasms usually originating in the gonads, most often affecting young patients. Intravascular GCTs are exceptionally rare and potentially fatal due to cardiac and embolic complications. CASE SUMMARY: A 17-year-old patient presented with weight loss, abdominal pain, and dyspnea. Imaging revealed an intravascular mass extending from the inferior vena cava (IVC) into the right heart chambers and pulmonary arteries. The tumor was successfully removed via surgery under cardiopulmonary bypass. Histopathologic diagnosis was a mixed non-seminomatous GCT. Recovery was uneventful, and follow-up imaging showed no intravascular lesions. Cisplatin-based chemotherapy was started with curative intent. DISCUSSION: Intravascular GCT is a rare phenomenon, presenting mostly with retroperitoneal disease affecting the IVC. Cardiologists assess complications and interpret cardiovascular imaging. A multidisciplinary approach is crucial for improving outcomes.