Abstract
BACKGROUND: Contrast-induced encephalopathy (CIE) is a rare neurological complication following the administration of contrast agents during angiographic procedures. However, it is often overlooked due to the lack of specificity in the clinical manifestations. CASE SUMMARY: An 85-year-old woman was diagnosed with acute ST-segment elevation myocardial infarction due to complete occlusion of the left anterior descending artery and was treated with percutaneous coronary intervention. Subsequently, she developed aphasia but recovered completely on her own approximately 60 hours later. DISCUSSION: CIE is an acute and reversible neurological disorder syndrome that occurs shortly after intravascular administration of contrast agents. The clinical manifestations are highly heterogeneous, which increases the difficulty of differential diagnosis. There is no specific treatment for CIE, and the main strategy is to maintain the stability of vital signs and improve the patient's symptoms. TAKE-HOME MESSAGE: CIE is a significant complication following intravascular administration of contrast agents.