Abstract
Multivalvular disease presents unique clinical challenges compared with isolated valve pathologies because they often involve altered hemodynamics and physiology. A common combination is aortic stenosis and mitral stenosis, which frequently coexist owing to rheumatic or degenerative etiologies. This case series explores 3 patients with concurrent severe symptomatic mitral stenosis and aortic stenosis, illustrating how management strategies can vary significantly based on the patient's surgical risk, symptom burden, and anatomical features. These cases illustrate the experiences at our institution in managing patients with double obstructions, and they emphasize the importance of accurate assessment of disease severity as well as the need for tailored interventional strategies. They highlight the gap in international guidelines for managing such complex multivalvular pathologies and underscore the necessity of a more structured and comprehensive approach to optimize patient outcomes.