Abstract
BACKGROUND: Up to 20% of patients with chronic limb-threatening ischemia (CLTI) are not eligible for conventional revascularization options despite having severe symptoms of nonhealing ulcers and gangrene. Transcatheter arterialization of the deep veins (TADV) has shown promising results in this challenging subset of patients. CASE SUMMARY: We present the long-term outcomes of 4 patients with no-option CLTI who were at risk of major below-the-knee amputation and were treated with TADV with the LimFlow System (Inari Medical). DISCUSSION: The PROMISE trials have reported positive outcomes at 12 months after TADV, and the long-term durability of TADV remains of great interest. The patients herein underwent successful TADV, with durable limb salvage through follow-up extending up to 8 years. TAKE-HOME MESSAGE: TADV with the LimFlow System provides durable limb salvage in no-option CLTI patients, with observed long-term wound healing and symptom healing.