Abstract
BACKGROUND: Behçet's disease (BD) is a systemic vasculitis with multisystem involvement, including rare but serious cardiovascular complications. Although venous manifestations are more common, arterial complications-particularly coronary artery aneurysms-are exceptionally rare and poorly documented. CASE SUMMARY: A 28-year-old man with BD in remission presented with acute chest pain. Work-up revealed a giant aneurysm of the left anterior descending coronary artery. He was treated with ischemic heart disease therapy and immunosuppressants in preparation for bypass surgery. DISCUSSION: Cardiovascular complications in BD, particularly coronary aneurysms, are rare but associated with significant morbidity. Their management is not well documented. Early diagnosis and multidisciplinary care are essential. TAKE-HOME MESSAGES: In patients with BD, cardiovascular symptoms warrant prompt and thorough evaluation. Collaborative management involving cardiologists, internal medicine physicians, and cardiothoracic surgeons is essential for timely and effective management.