Abstract
BACKGROUND: A 41-year-old woman presented with chest pain and dyspnea progressively worsening over a year. Examination revealed an ejection systolic murmur, and imaging identified the right ventricular mass, suspected to be a myxoma. CASE SUMMARY: Transthoracic echocardiography revealed a right ventricular echogenic mass with severe tricuspid regurgitation, confirmed using computed tomography and magnetic resonance imaging. The patient underwent surgical excision of the mass with tricuspid valve replacement. Histopathologic examination confirmed a myxoma. Postoperatively, the patient required pacemaker implantation but showed considerable symptomatic improvement with no recurrence on follow-up. DISCUSSION: Myxomas are the most common primary cardiac tumors in adults. Multimodal imaging is crucial for diagnosis and treatment planning. Complete surgical resection can achieve optimal outcomes. TAKE-HOME MESSAGES: Myxomas are the most common primary cardiac tumors in adults. Multimodal facilitates accurate diagnosis and treatment planning, while complete surgical resection remains the definitive management strategy.