Extensive Calcification of the Ventricular Septum in Gene-Positive (MYBPC3) Nonobstructive Hypertrophic Cardiomyopathy

基因阳性(MYBPC3)非梗阻性肥厚型心肌病患者室间隔广泛钙化

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Abstract

IMAGES: We present multimodality imaging of ventricular septal calcification. CASE SUMMARY: A 38-year-old man with asymptomatic gene-positive hypertrophic cardiomyopathy was found to have extensive dystrophic calcification of the ventricular septum. We hypothesized that the extensive ventricular septal calcification would represent an area of severe myocardial fibrosis, resulting in calcification secondary to postsurgical (septal myectomy) changes. TAKE-HOME MESSAGE: Calcification of the ventricular septum is a rare finding, not previously described following septal myectomy, that should prompt a comprehensive evaluation and follow-up with multimodality imaging and testing.

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