Abstract
Diffuse large B-cell lymphoma (DLBCL) of the heart is an extremely rare and life-threatening condition. Given its location and invasive nature, surgical resection can be highly challenging. Multimodality imaging, including 3-dimensional printing, and a multidisciplinary approach are crucial for surgical planning and successful management. We present a unique case of a large, compressing, symptomatic pericardial mass that was surgically resected. The diagnosis was confirmed as DLBCL. Through the effective use of advanced imaging techniques and state-of-the-art surgical planning and execution, the tumor was successfully resected, leading to an accurate diagnosis and the potential for further treatment. This procedure resulted in symptom relief and an improved quality of life for the patient.