Abstract
Aspergillus endocarditis is a rare condition. The clinical presentation is often atypical and insidious, resulting in delayed diagnosis and challenges in management. We report a case of native mitral valve Aspergillus endocarditis in an immunocompetent patient, with rare aortal embolization, who was managed in a multidisciplinary approach. Evidence for Aspergillus endocarditis is limited, and prospective data are unlikely to be available because of the low incidence of the disease. This case report adds great value to the current published case series to provide experience for clinicians when tackling similar conditions. Aspergillus endocarditis is rare but fatal. Cardiac surgery improves early survival, but long-term outcomes remain dismal. An endocarditis team with a multimodality approach is paramount to manage this difficult-to-treat disease.