Abstract
This paper presents a case of acute myocardial infarction in a patient with a thrombotic occlusion of a diffusely diseased left anterior descending artery, who also had nonculprit severe lesions in the obtuse marginal and right coronary arteries. Considering the extent of the disease and the clinical presentation, a carefully planned multistaged hybrid approach involving drug-eluting balloons and stents was chosen as the optimal revascularization strategy for this patient.