Good performance of immunoglobulin M assays in diagnosing genotype 3 hepatitis E virus infections

免疫球蛋白M检测在诊断3型戊型肝炎病毒感染方面表现良好

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Abstract

We have evaluated three anti-hepatitis E virus (anti-HEV) immunoglobulin M (IgM) assays, the EIAgen HEV IgM assay (Adaltis), the HEV IgM enzyme-linked immunosorbent assay 3.0, and the Assure HEV IgM rapid test (MP Diagnostics), for the routine detection of acute genotype 3 HEV. Their sensitivities were fairly good (90%, 88%, and 82%), and their specificities were excellent (100%, 99.5%, and 100%).

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