Immunogenicity associated with the routine use of an influenza A H1N1 vaccine in health care personnel in Guangzhou, China

中国广州医护人员常规使用甲型H1N1流感疫苗的免疫原性研究

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Abstract

We present immunogenicity data on the routine vaccination of 103 health care personnel during the 2009 H1N1 national vaccination campaign. The seroprotection rate (percentage of samples with hemagglutination inhibition titers of > or =1:40) was 83.2% at 30 days postvaccination, lower than those obtained in previously published controlled trials. Low baseline antibody levels and an increase in seroprotection in a negative-control cohort suggest that the virus remains prevalent.

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