Abstract
Contrast-enhanced mammography (CEM) has increasingly been established as a valuable tool in breast imaging that enhances lesion detection and characterization by combining functional and anatomical information. This review highlights the recent key advances in CEM technology, explores its expanding clinical applications, and discusses the common interpretation pitfalls and current limitations. Instead of offering a comprehensive overview, this review focuses on providing a case-based perspective on emerging applications and how CEM can be efficiently incorporated into clinical practice. Through illustrative case examples, we offer practical insights into optimizing breast imaging strategies and demonstrate how CEM can effectively complement other imaging modalities in both routine practice and complex diagnostic scenarios.