Individualized positive end-expiratory pressure with and without recruitment maneuvers in obese patients during bariatric surgery

在肥胖患者接受减肥手术期间,采用个体化的呼气末正压通气(伴或不伴肺复张手法)

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Abstract

This study aimed to determine whether regular recruitment maneuvers (RMs) are essential for obese patients (OPs) undergoing elective laparoscopic bariatric surgery (LBS) during intraoperative ventilation with individualized positive end-expiratory pressure (PEEP). Patients were randomly assigned to two arms: the RM + PEEP(-EIT) arm consisted of individualized PEEP titrated by electrical impedance tomography (EIT) with two regular RMs and the PEEP(-EIT) arm consisted of individualized PEEP titrated by EIT without additional RMs. For these two arms together, EIT-guided PEEP varied among individuals. The partial pressure of oxygen in arterial blood to fractional inspired oxygen (PaO(2) /FiO(2) ) ratio in the RM + PEEP(-EIT) arm was higher than that in the PEEP(-EIT) arm at 1 h after pneumoperitoneum (p = 0.024) and at the end of surgery (p = 0.035). There was no great difference in the PaO(2) /FiO(2) ratio between these two arms when measured 5 min prior to postanesthesia care unit (PACU) departure and on postoperative day 1. Compared with the PEEP(-EIT) arm, patients in the RM + PEEP(-EIT) arm had significantly higher intraoperative dynamic respiratory system compliance (p < 0.001) but consumed more vasopressors (p = 0.036). Postoperative pulmonary complications occurred in 1 of 29 patients in the RM + PEEP(-EIT) arm compared with 2 of 31 patients in the PEEP(-EIT) arm. Regular lung RMs can improve intraoperative oxygenation and respiratory system compliance among OPs undergoing LBS with EIT-guided individual PEEP. However, the improvement might disappear before leaving the PACU, and regular RMs resulted in more vasopressor consumption.

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