Delayed-type hypersensitivity responses in mice infected with St. Louis encephalitis virus: kinetics of the response and effects of immunoregulatory agents

感染圣路易斯脑炎病毒的小鼠的迟发型超敏反应:反应动力学及免疫调节剂的作用

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Abstract

Labeled monocyte infiltration techniques have been used to study delayed-type hypersensitivity responses in mice immunized with St. Louis encephalitis virus. A delayed 24- to 48-h inflammatory response occurred 6 to 7 days after immunization. This response can be potentiated by cyclophosphamide treatment, by BCG administration, or by splenectomy. Treatments known to selectivity inhibit T-cell function suppressed the response.

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