Abstract
The aim of this study was to evaluate astigmatic correction in patients with mild to moderate astigmatism after combined femtosecond laser-assisted cataract surgery (FLACS) and intrastromal arcuate keratotomy (ISAK), using vector analysis. This retrospective study included patients with corneal astigmatism of 0.5-3.0 diopters (D) who underwent FLACS and ISAK. Vector analyses of astigmatism were performed using the Alpins method, considering three vectors: target-induced astigmatism (TIA), surgically induced astigmatism (SIA), and difference vector (DV). Magnitude of error (ME), angle of error (AE), correction index (CI), and coefficient of adjustment (CA) were calculated. Subgroup analysis according to the axis of astigmatism, patient age, and white to white (WTW) diameter was conducted. In total, for the 79 eyes of 79 patients, the TIA was 1.21 ± 0.52 D, the SIA was 0.76 ± 0.53 D, and the DV was 0.86 ± 0.50 D. The ME (difference between SIA and TIA) was -0.46 ± 0.45 D, and the CI (ratio of SIA and TIA) was 0.62 ± 0.34; both these parameters demonstrated slight undercorrection. The CA (inverse of the CI) was 2.48 ± 2.61. The AE was 4.02° ± 28.7°, and the absolute AE was 21.7° ± 19.0°. In the univariate regression analyses to identify factors that affected the CI, there was a negative correlation between age and the CI (P=0.022). In conclusion, vector analysis after the combined FLACS and ISAK revealed slight undercorrection, regardless of the astigmatism meridian. The precision of the nomogram should be improved through long-term vector analysis for the results of arcuate keratotomy and through further research on the relationship between patient demographics and CI. Overall, this study has shown that FLACS and ISAK could reduce postoperative corneal astigmatism effectively and safely.