Altered expression of Sialyl Lewis X in experimental models of Parkinson's disease
帕金森病实验模型中唾液酸路易斯 X 表达的改变
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作者：Maria João Nunes, Andreia Neves Carvalho, Alexandra I Rosa, Paula A Videira #, Maria João Gama, Elsa Rodrigues, Margarida Castro-Caldas #
Key messages
MPTP triggers the presentation of proteins decorated with sLeX in mouse brain. MPTP triggers the expression of sLeX rate-limiting enzyme FUT 7 in striatum. sLeX is expressed in neurons, including dopaminergic neurons, and microglia. sLeX in the brain may have a role in neuronal signalling and immunomodulation.
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