Abstract
BACKGROUND: In Emergency Departments (EDs), triage is crucial for determining patient severity and prioritizing care, typically using the Manchester Triage Scale (MTS). Traditional triage systems, reliant on human judgment, are prone to under-triage and over-triage, resulting in variability, bias, and incorrect patient classification. Studies suggest that Machine Learning (ML) and Natural Language Processing (NLP) could enhance triage accuracy and consistency. This review analyzes studies on ML and/or NLP algorithms for ED patient triage. METHODS: Following Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines, we conducted a systematic review across five databases: Web of Science, PubMed, Scopus, IEEE Xplore, and ACM Digital Library, from their inception of each database to October 2023. The risk of bias was assessed using the Prediction model Risk of Bias Assessment Tool (PROBAST). Only articles employing at least one ML and/or NLP method for patient triage classification were included. RESULTS: Sixty studies covering 57 ML algorithms were included. Logistic Regression (LR) was the most used model, while eXtreme Gradient Boosting (XGBoost), decision tree-based algorithms with Gradient Boosting (GB), and Deep Neural Networks (DNNs) showed superior performance. Frequent predictive variables included demographics and vital signs, with oxygen saturation, chief complaints, systolic blood pressure, age, and mode of arrival being the most retained. The ML algorithms showed significant bias risk due to critical bias assessment in classification models. CONCLUSION: NLP methods improved ML algorithms' classification capability using triage nursing and medical notes and structured clinical data compared to algorithms using only structured data. Feature engineering (FE) and class imbalance correction methods enhanced ML workflows' performance, but FE and eXplainable Artificial Intelligence (XAI) were underexplored in this field. Registration and funding. This systematic review has been registered (registration number: CRD42024604529) in the International Prospective Register of Systematic Reviews (PROSPERO) and can be accessed online at the following URL: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=604529 . Funding for this work was provided by the National Council for Scientific and Technological Development (CNPq), Brazil.