Abstract
Little is documented about the frequency and management of allergic reactions to hypoglossal nerve stimulator implants. This case report describes a 69-year-old female with obstructive sleep apnea who received a hypoglossal nerve stimulator device and had an adverse reaction concerning for an allergic reaction to the medical device. The complication was managed via topical steroids, and although the patient's symptoms initially resolved she experiences continued intermittent maculopapular pruritic rashes approximately once per week. This case report details the patient's presentation, including progression and management, while also highlighting the diagnostic challenges in identifying allergic reactions to medical implants and offering considerations for future management. CITATION: Gouldman KP, Yu JL. Allergic reaction to hypoglossal nerve stimulator: a case report. J Clin Sleep Med. 2025;21(1):211-213.