Abstract
Critical appraisal plays a key role in assessing the credibility of scientific research, particularly in evidence-based practice, where it guides clinical decision-making and informs the effective application of evidence in practice. This study aimed to critically evaluate research on the knowledge and attitudes of healthcare professionals toward human papillomavirus vaccination. Published cross-sectional studies on the knowledge and attitudes of healthcare professionals about HPV vaccination from 2006 to December 2023 were collected using databases including PubMed, Scopus, Science Direct, as well as Google Scholar search engine and critically evaluated. The quality of these studies was assessed using the Statement of Strengthening the Report of Observational Studies in Epidemiology. The overall compliance of study reports with STROBE statement items was 60.69%. The per-article compliance scores ranged from 32% to 76%. The most common weakness was found in the results section (49.27%). The introduction and discussion had the highest quality (84.78% and 80.43% respectively). The reporting quality of published articles on healthcare professionals' knowledge and attitudes toward HPV vaccination needs improvement. Journals should enforce policies to ensure compliance with reporting standards.