Abstract
This case report describes the treatment of a 9-year-old boy with advanced adrenoleukodystrophy (ALD) who received radioelectric asymmetric conveyer (REAC) neuro-regenerative (RGN-N) therapy after hematopoietic stem cell transplantation (HSCT) failed to produce therapeutic benefits. ALD is a devastating neurodegenerative disorder for which limited treatment options exist, and interventions are often ineffective in advanced cases. Post-transplant, the patient's symptoms worsened until REAC RGN-N therapy was introduced. After treatment, notable improvements were observed in motor function, swallowing, spasticity, and overall quality of life. These results suggest that REAC RGN-N treatment may be an effective intervention to slow neurodegenerative progression and support recovery in ALD cases unresponsive to HSCT.