Antimycobacterial potentials of quercetin and rutin against Mycobacterium tuberculosis H37Rv

槲皮素和芦丁对结核分枝杆菌H37Rv的抗分枝杆菌活性

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Abstract

Quercetin and rutin, two flavonoids were examined for antimycobacterial activities against M. tuberculosis H37Rv (ATCC 27294). The quercetin exhibited (99.30 ± 0.268%) in (LRP) assay at 200 µg/ml and 56.21 ± 0.97% inhibition in (BMD) at 50 µg/ml, whereas rutin exhibited (90.40 ± 0.68%) in LRP assay at 200 µg/ml and 56.10 ± 0.67% inhibition in BMD at 50 µg/ml. The minimum inhibitory concentration (MIC) was found to be 6.25 µg ml(-1) and 25 µg ml(-1) respectively. The current investigation suggests that quercetin has better inhibitory activity than rutin.

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