Abstract
Malignant neoplasms of the chest wall often require radical resection, leaving large defects in which soft tissue coverage alone is inadequate. Reconstruction of these defects must provide structural support to protect thoracic viscera, to reestablish adequate respiratory function, and to achieve acceptable cosmetic outcomes. Techniques described in the literature are varied, and there is no consensus on best practices. We present 3 cases of large chest wall defects that were reconstructed by a method in which titanium mesh is sandwiched between sheets of porcine acellular dermal matrix. We find this method safe and applicable to large anterior defects.