Abstract
OBJECTIVES: Although cardiovascular disease (CVD) is responsible for a large global burden of disease, a large proportion of CVD incidence can be prevented through health literacy (ie, the skills and resources of an individual to access, understand, and use information to make decisions and act on one's own health and health care). We reviewed and synthesized peer-reviewed literature on health literacy and primary prevention of CVD. METHODS: We followed methods from the review's previously published protocol, which outlined a search strategy conducted on August 16, 2024, for 6 databases, linking concepts of health literacy and CVD risk and its associated knowledge, attitudes, or practices. One reviewer screened and extracted all articles, and a second reviewer screened a randomly selected 10% of articles at each stage to examine interrater agreement. We used the Office of Health Assessment and Translation Risk of Bias Tool to assess the potential risk of bias. RESULTS: Of 35 studies in the synthesis, 26 (74%) were cross-sectional and 21 (60%) measured functional health literacy only. Twenty-three articles investigated health literacy as an exposure variable, 20 of which reported significant results. Eight articles examined the administration of health literacy interventions to populations at risk of CVD, and 4 presented health literacy profiles of populations at risk of CVD. Each study demonstrated at least 1 area of potential risk of bias but was deemed low risk of bias overall. CONCLUSIONS: Several studies in this review found an association between health literacy and CVD risk. More longitudinal studies, as well as studies that measure health literacy more deeply than simply reading and comprehending health texts, are needed to better understand the extent of this relationship.