Abstract
OBJECTIVE: To explore the distribution characteristics of population with positive anti-gliadin antibody (AGA) and anti-Saccharomyces cerevisiae antibody (ASCA), reveal the important value of early detection of AGA and ASCA. METHODOLOGY: This is a retrospective comparative analysis. Comparative analysis of AGA and ASCA detected data in Baoding No.1 Central Hospital from February 2021 to February 2024. The rate between groups was compared by χ(2) test. P<0.01 was considered as statistically significant. RESULTS: The ratio of male to female was 1:1.4. The number of male patients with AGA positive was significantly lower than that of females (χ(2)=88.76, P<0.01). Among the 1286 patients with ASCA positive, there were 726 males and 560 females. The ratio of male to female was 1:0.77. The number of male patients with AGA positive was significantly higher than that of females (χ(2)=42.86,P<0. 01). There are great differences in the distribution of AGA and ASCA between different genders. With the increase of age, the positive rate of AGA showed a downward trend and ASCA showed an upward trend. There are great differences in the distribution trend of AGA and ASCA with age. CONCLUSION: Early detection of AGA and ASCA have definite guiding significance for early diagnosis and differential diagnosis of digestive diseases to reduce misdiagnosis and missed diagnosis.