Abstract
BACKGROUND: Endoscopic cold snare resection (CSP) can enhance postoperative recovery and minimize bleeding risk in patients with 5-15 mm colorectal polyps. However, more detailed evaluations are required to assess their advantages over conventional methods. AIM: To evaluate the effects of endoscopic CSP on postoperative recovery and bleeding risk in patients with 5-15 mm colorectal polyps. METHODS: This randomized controlled study included 193 patients (mean age: 57.91 ± 5.41 years; 97 men and 96 women) with 5-15 mm colorectal polyps treated at Dongyang People's Hospital between March and June 2023. The patients were randomly assigned to the experimental group (n = 100), who underwent CSP, and the control group (n = 93), who underwent conventional endoscopic mucosal resection (EMR). Operation time, hospital stay, dietary status, and bleeding rate within 3 days were compared. RESULTS: The CSP group had significantly shorter operation times (15.02 ± 2.44 minutes vs 18.78 ± 5.48 minutes, P < 0.001) and hospital stays (3.11 ± 1.08 days vs 4.89 ± 1.35 days, P < 0.001) than the EMR group. The fasting rate on the day of surgery was also lower in the CSP group (P < 0.05). The complete resection rates were similar between groups (98.00% vs 94.62%, P = 0.210), and no perforations occurred in either group. The 3-day postoperative bleeding rate was slightly lower in the CSP group (2.00%) than in the EMR group (6.45%), although this difference was not statistically significant (P = 0.234), indicating limited clinical relevance. CONCLUSION: CSP was safe and efficient for removing 5-15 mm colorectal polyps, offering faster recovery and comparable safety to EMR. The procedural efficiency of CSP supports its broad clinical application.