Mechanoreceptors in collateral knee ligaments: an animal experiment

膝关节侧副韧带中的机械感受器:一项动物实验

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Abstract

The mechanoreceptors in the collateral ligaments of the knee joint in rat hindlimbs were studied. In group II (n=10) the femoral and obturator nerves were sectioned. In both groups III and V (n=20) the sciatic nerve was sectioned. In group V (n=10) the sectioned sciatic nerve was sutured 4 weeks after sectioning. In group IV (n=10) all three nerves were sectioned. Group I (n=10) served as control. After 4 months all animals were killed. The ligaments of the knee joint were preserved and stained with gold chloride, paraffin-embedded and cut in sagittal serial sections. The results showed that 4 months after partial or total denervation of the limb, there was necrosis and a decrease in the number of mechanoreceptors, which was dependent upon the severity and site of the lesion. After suture of the sciatic nerve the increase in mechanoreceptors suggested a regenerative process.

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