Hatched and starved: Two chromatin compaction mechanisms join forces to silence germ cell genome

孵化后饥饿:两种染色质压缩机制联手沉默生殖细胞基因组

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Abstract

Animals evolved in environments with variable nutrient availability and one form of adaptation is the delay of reproduction in food shortage conditions. Belew et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202009197) report that in the nematode C. elegans, starvation-induced transcriptional quiescence in germ cells is achieved through a pathway that combines two well-known chromatin compaction mechanisms.

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