Single-Step First Trimester Screening "Sooner the Better"

单步式孕早期筛查“越早越好”

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Abstract

PURPOSE: To evaluate the role of single-step universal screening in first trimester and its effectiveness. MATERIALS AND METHODS: Three thousand women attending antenatal clinic of Pt JNM Medical College, Raipur, were screened with 75 gm OGTT in their first trimester irrespective of their last meal, and those who were screened negative were again subjected to OGTT at 24-28 weeks. The women were followed throughout pregnancy till delivery. Any maternal or perinatal complications were noted. RESULT: Overall incidence of GDM was 5.2 %. About 61.54 % women screened positive in first trimester. At 24-28 weeks, 38.46 % women were diagnosed with GDM. Women diagnosed in first trimester showed significantly low incidence of cesarean section rate (20.83 %), PIH (2.08 %), and macrosomia (14.44 %), in comparison to women diagnosed later in pregnancy. CONCLUSION: The role of first trimester screening was found effective in reducing adverse maternal and perinatal outcomes in GDM.

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