Data in support of 5'AMP-activated protein kinase alpha regulates stress granule biogenesis

支持 5'AMP 活化蛋白激酶 α 调节应激颗粒生物合成的数据

阅读:14
作者:Hicham Mahboubi, Ramla Barisé, Ursula Stochaj

Abstract

This data article contains insights into the regulation of cytoplasmic stress granules (SGs) by 5'-AMP-activated kinase (AMPK). Our results verify the specific association of AMPK-α2, but not AMPK-α1, with SGs. We also provide validation data for the isoform-specific recruitment of the AMPK-α subunit to SGs using (i) different antibodies and (ii) a distinct cellular model system. In addition, we assess the SG association of the regulatory AMPK β- and γ-subunits. The interpretation of these data and further extensive insights into the regulation of SG biogenesis by AMPK can be found in "5'AMP-activated protein kinase alpha regulates stress granule biogenesis" [1].

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。