Comparative Study of Mifepristone with Vaginal Misoprostol for First Trimester Termination of Pregnancy at Different Gestational Ages

米非司酮与阴道用米索前列醇在不同孕周终止妊娠早期疗效的比较研究

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Abstract

METHODS: This study for medical abortion was conducted in the Department of Obstetrics and Gynaecology, Zenana Hospital, SMS Medical College, Jaipur during 2011-2012. In total 280 cases were taken for the study and divided into two groups, among whom there were six defaulters in each group who failed to present for follow-up. OBJECTIVES: The objectives of this study were to (1) compare the success rates of abortion at different gestational ages, (2) study the side effects of the drugs, and (3) study the acceptability in both the groups. RESULTS: The medical abortion with the given regimen and protocol was observed to be highly successful, and complete abortion was achieved in 98.51 and 97.76 % of the patients in Group-A and Group-B, respectively. Failure rates observed were only 1.49 % in Group-A and 2.24 % in Group-B. CONCLUSIONS: Medical abortion can be safely performed in cases up to 63 days of gestation, but women should be counseled about the increased blood loss and duration of bleeding.

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