Role of Serum Magnesium as Predictor of Preeclampsia

血清镁在预测先兆子痫中的作用

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Abstract

BACKGROUND: Preeclampsia is best described as a pregnancy specific syndrome that can affect virtually every organ system. Even though a multitude of novel markers are available, serum magnesium is a cost-effective method in prediction of preedampsia. The aim of the study is to find out the relationship between serum magnesium and preeclampsia and its role in prediction of the same. METHODS: This is a comparative study done over a period of 18 months including antenatal women at 32 weeks period of gestation with 60 participants in each group with BP recording of > 140/90 mmHg as cases and < 140/90 mmHg as controls and serum magnesium levels were compared. RESULTS: Mean serum magnesium (1.82 ± 0.26) levels were noted to be lower in preeclampsia group (p value < 0.001), whereas the mean age (32.4 ± 4.4) and BMI (29.7 ± 1.9) in the preeclampsia group were higher than that in normotensive group. CONCLUSION: This study shows that detection of serum magnesium can be cost-effective method for prediction of preeclampsia and its supplementation in pregnancy can aid in prevention as well.

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