Isolation and Characterization of a Novel Achromobacter Strain from a Diarrheal Stool Specimen

从腹泻粪便标本中分离和鉴定一种新型无色杆菌菌株

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Abstract

A novel bacterial strain, designated as L3024hy, was isolated from the fecal matter of a patient suffering from diarrhea in China. Whole-genome sequencing has identified this strain as a member of the genus Achromobacter. Comparative genomic analyses, including Average Nucleotide Identity (ANI) and digital DNA-DNA hybridization (dDDH), indicated that L3024hy constitutes a distinct lineage within this genus, as evidenced by ANI and dDDH values falling below established thresholds for species demarcation. This strain harbors multiple virulence genes associated with host colonization, suggesting its potential clinical significance. This study underscores the increasing diversity of the genus Achromobacter and emphasizes the necessity for further research on its role in human infections.

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