Abstract
BACKGROUND: This case report aims to evaluate the feasibility of medical and surgical management in a patient with invasive bronchopulmonary mucormycosis complicated by renal insufficiency-a critical challenge limiting antifungal dosing and requiring tailored therapeutic strategies, while also reviewing the current literature on the treatment of pulmonary mucormycosis. CASE PRESENTATION: The patient received low-dose antifungal therapy with posaconazole and amphotericin B cholesterol sulfate complex. Subsequently, the patient underwent a left inferior lobectomy and experienced a successful postoperative recovery. Renal insufficiency complicates drug selection and dosing. A literature review demonstrated that combining antifungal therapy with surgical intervention is an effective approach for treating invasive bronchopulmonary mucormycosis. CONCLUSION: The combination of antifungal therapy and surgical management proves to be an effective treatment strategy for invasive bronchopulmonary mucormycosis in patients with renal insufficiency.