Abstract
We present a case of Stenotrophomonas maltophilia-induced soft tissue infection in a patient with acute myeloid leukemia (AML), who exhibited atypical symptoms and lab findings. The patient fully recovered following ultrasound-guided drainage and appropriate medical intervention. Due to Stenotrophomonas maltophilia's multi-drug resistance and high mortality rate, we share this case to highlight the importance of timely diagnosis and treatment for this aggressive infection in immunocompromised individuals.