Characteristics of HPV Infection in Women Cervical and Anal with HIV-Infected and the Advances in Epidemiological Research

HIV感染女性宫颈和肛门HPV感染的特征及流行病学研究进展

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Abstract

Antiretroviral therapy (ART) has significantly reduced the incidence and mortality of AIDS-related diseases, bringing the life expectancy of human immunodeficiency virus (HIV)-infected individuals close to that of uninfected individuals. However, the incidence and mortality rates of tumors associated with human papillomavirus (HPV) have not decreased. Persistent infection with high-risk HPV is a major cause of cervical cancer and other related malignancies, and the risk of HPV infection and the incidence of related diseases are higher among HIV-infected individuals. Although the World Health Organization provides screening recommendations for the general population, there is a lack of guidelines for cervical and anal cancer screening specifically in HIV-positive patients. Further research is urgently needed to develop effective preventive measures. This article reviews the epidemiological characteristics and associations of HPV infections and related cancers in HIV-infected women, providing reference for prevention and treatment.

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