Abstract
In this report, we analyze the trends in antimicrobial resistance of Staphylococcus aureus according to the last 15-year-period reports of the China Antimicrobial Surveillance Network (CHINET). It is encouraging that there is a decreasing MRSA proportion in the infection of adults as well as better activity of non-beta-lactam agents in vitro in recent years. However, childhood MRSA infection as well as the tigecycline-resistant MRSA isolate in China deserves increasing concern.