Abstract
Air pollution is a major global health threat, with exposure exhibiting substantial heterogeneity across and within regions. While disparities in air pollution exposure by income groups are well documented, how these inequalities translate into differential burdens of pollution-attributable premature mortality remains understudied. We utilize high-resolution estimates of secondary air pollutants, combined with income data, to investigate the relationship between global air pollution-attributable mortality and poverty across urban-rural contexts and air pollutants. We show that high-income countries face higher air pollution-attributable mortality owing to population aging, in contrast to the established exposure inequality pattern. While affluent populations within most countries also face higher mortality burdens, in several low-income countries, this pattern is reversed due to elevated exposures among impoverished rural populations. South Asia and Africa exhibit the highest levels of vulnerability to coincident mortality and poverty, where populations living in periurban transition zones bear disproportionate dual burdens. In many low-income countries, those living near wealthier urban centers also face elevated health burdens from air pollution: a "cost of opportunity" when air pollutant regulations are weak. Our findings emphasize the imperative for tailored policy interventions to mitigate amplified health risks in vulnerable communities.