Population genetics of Mycobacterium tuberculosis complex in Scotland analysed by pulsed-field gel electrophoresis

利用脉冲场凝胶电泳分析苏格兰结核分枝杆菌复合群的群体遗传学

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Abstract

The results of typing of 121 strains in the Mycobacterium tuberculosis complex by PFGE are presented. Every isolate from patients in Scotland over a 3-month period for M. tuberculosis and for 1 year for M. bovis were included along with several laboratory strains including those of BCG. The PFGE results suggest that the population structure of all the strains in this complex is distinctly simple with limited genetic diversity and also suggest that M. bovis is not a distinct species.

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