Imprime PGG, a yeast β-glucan immunomodulator, has the potential to repolarize human monocyte-derived M2 macrophages to M1 phenotype

Imprime PGG 是一种酵母β-葡聚糖免疫调节剂，具有将人单核细胞来源的M2巨噬细胞重新极化为M1表型的潜力。

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作者：Janetzki,Sylvia,Andtbacka,Robert HI,Collichio,Frances A,Amatruda,Thomas,Senzer,Neil,Chesney,Jason,Delman,Keith,Spitler,Lynn,Puzanov,Igor,Agarwala,Sanjiv,Milhem,Mohammed,Harrington,Kevin,Middleton,Mark,Li,Ai,Shilkrut,Mark,Coffin,Robert,Kaufman,Howard,Miller,Lance D,Chou,Jeff W,Black,Michael A,Print,Cristin G,Jimenez,Eric,Chifman,Julia,Alistar,Angela,Putti,Thomas C,Zhou,Xiaobo,Bedognetti,Davide,Pullikuth,Ashok,Andrechek,Eran,Wang,Ena,Marincola,Francesco M,Chan,Anissa SH,Qiu,Xiaohong,Jonas,Adria Bykowski,Patchen,Myra L,Bose,Nandita
期刊：Journal for ImmunoTherapy of Cancer影响因子：10.600
时间：2014起止号：2014;2(Suppl 3):P191
doi：10.1186/s40425-015-0074-0研究方向： 细胞生物学、免疫/内分泌
细胞类型： 巨噬细胞、单核细胞

Abstract

Investigators from academia and industry gathered on August 14, 2014, in Boston at the Inaugural ImVacS conference entitled “Target Discovery for T Cell Therapy: Next Step to Advance Immunotherapies”. Novel targets, discovery strategies and enabling technologies were presented and discussed.

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