Abstract
This is a protocol for a Cochrane Review (overview). The objectives are as follows: To summarise Cochrane Neonatal evidence on: 1. interventions (pharmacological or surgical) for prevention of PDA and related complications in preterm infants; and 2. interventions (pharmacological or surgical) for management of PDA in preterm infants, including: a. interventions for management of asymptomatic PDA in preterm infants; and b. interventions for management of symptomatic (haemodynamically significant) PDA in preterm infants.