Abstract
BACKGROUND: Follicular thyroid carcinoma (ftc) is a malignant neoplasm arising from thyroid follicular epithelial cells and is the second most common thyroid cancer after papillary thyroid carcinoma. meningeal metastasis from ftc with calvarial destruction is exceedingly rare and is often misdiagnosed clinically as meningioma. we reviewed previously reported cases in the literature and, in addition, report and include one case of meningeal metastasis from ftc treated at our center. METHODS: Using the keywords "meningioma," "follicular thyroid carcinoma," and "cerebral metastatic tumor," we searched PubMed/MEDLINE and Web of Science to identify relevant publications. We extracted patient age, sex, tumor location and size, treatment modalities, and follow-up outcomes. In parallel, we provide a detailed description and analysis of the clinical course of the present case. RESULTS: A total of 10 patients were included, comprising the cases reported in the literature and the index case in this study. The mean age was 60.5 years, and most lesions were solitary epidural or dural-based masses. Headache was the most common presenting symptom. All patients underwent surgical resection; postoperative recurrence occurred in two cases, and the longest survival on follow-up was 7 years. CONCLUSIONS: Meningeal metastasis from FTC is rare and typically presents as a dural-based mass that readily mimics meningioma. Gross-total resection can achieve favorable initial disease control, although recurrence may still occur. Given the small number of reported cases, the long-term prognosis remains uncertain and warrants further investigation.